Longevity Is a Scientific and Societal Paradigm Shift

At its inaugural Longevity event at Le Visionnaire in Paris on June 10, 2025, L'Oréal Groupe established beauty as one of the fundamental pillars of longevity, demonstrating that skin health is a vital part of a longer, healthier life. Backed by new cutting-edge science shifting focus from symptom correction to root causes intervention, L'Oréal revealed its L'Oréal Longevity Integrative Science™ to empower consumers to move from corrective care to preventive care.

Biological Age: The New Truth

For decades, chronological age has defined our relationship with aging. L'Oréal's vision shifts that paradigm entirely. Biological age—determined by your biology and your choices—now defines your beauty journey.

According to Vania Lacascade, Chief Innovation Officer at L'Oréal Groupe: "Biological age is the new truth! Moving beyond chronological age as the sole defining factor. It's your biology – and your choices – that define your beauty journey. L'Oréal Longevity Integrative Science™ empowers you to design your unique, lifelong skin health journey – preventing, regenerating, or embracing the marks of time, at every age."

Three Pillars of L'Oréal Longevity Integrative Science™

L'Oréal's integrative approach to beauty longevity is founded on three core pillars:

• Root Cause Intervention. L'Oréal Longevity Integrative Science™ explores how cellular activity, communication, and inflammation impact skin aging, targeting the root causes of biological aging through a multi-faceted approach for extending skin cellular health span.

• The Wheel of Longevity for Beauty. After 15 years of advanced research on longevity and over 40 publications, L'Oréal has created the "Wheel of Longevity for Beauty" to decode skin aging at the cellular, molecular and tissular levels, unlocking secrets of the nine interconnected hallmarks of aging using their proprietary Longevity AI Cloud™.

• Longevity AI Cloud™. The unique Longevity AI Cloud™ analyzes over 260 skin longevity biomarkers, revealing the intricate mechanisms influencing skin vitality and youthfulness, even detecting infinitely small, invisible changes. This comprehensive bio-mapping of skin and hair longevity pathways is a first in the beauty industry, stemming from computational biology.

Advanced Diagnostics & Breakthrough Actives

L'Oréal's Longevity Integrative Solutions include state-of-the-art diagnostics and highly performant products formulated with exclusive combinations of actives, giving consumers more choice and more control over their longevity journey.

With Advanced Diagnostic Tools

• Cell BioPrint. Co-developed with NanoEntek, Cell BioPrint uses lab-on-a-chip technology to measure longevity biomarkers under the skin in less than five minutes. This knowledge empowers consumers to take charge of their skin health and influence their personal skin aging trajectory.

• Tru Diagnostic. L'Oréal's partnership with experts in epigenetic testing explores the link between beauty and epigenetics, or changes in gene expression, paving the way for innovations that promote the long-term health of the skin and hair.

With New Actives & Ingredients

• Timeline & Mitopure®. The Swiss Biotech company, Timeline, has developed a proprietary molecule, Mitopure®, that recycles and rejuvenates aging mitochondria, the powerhouses of cells. Backed by more than a decade of research and multiple gold standard clinical studies, this breakthrough technology is protected by an unparalleled intellectual property portfolio. In 2024, L'Oréal acquired a minority stake in Timeline through its strategic venture capital fund, BOLD. Timeline was recently named a Milestone 1 award winner for the XPRIZE Healthspan competition.

• Bio-actives Partnership. A strategic partnership with biotech Veminsyn will help discover, develop and scale innovative longevity bio-actives and cosmetic ingredients with low-carbon biomanufacturing.

With Consumer Product Innovations

• Lancôme Absolue Longevity Soft Cream. Inspired by groundbreaking skin booster technology of PDRN, a bio-stimulator at the forefront of regenerative aesthetics in South Korea, Lancôme Absolue PDRN™ can target cells and multiply mitochondria, the cell's powerhouse, responsible for 90% of cellular energy. Exclusive and protected by 7 patents until 2044, PDRN augments cell longevity metabolism to extend skin's youth.

• Vichy Laboratoires Neovadiol Longevity Revolumizing Cream. Powered by Longevisia Technology, a patent-pending combination of redensifying Proxylane, cell-energizing NAD+ Booster, and zombie-cell-killing Senevisium that resets 6 key hallmarks at the root of mature skin aging and restores cells' own power to recreate +31% more youthful skin tissue.

Building the Longevity Integrative Ecosystem

The L'Oréal Longevity Integrative Ecosystem merges L'Oréal's advanced research with an external ecosystem of leading partners in longevity science. This open innovation, integrative approach accelerates knowledge, fuels the discovery of new actives and innovative beauty combos, and powers the development of cutting-edge predictive diagnostic tools.

Research partnerships include collaborations with Senisca, an award-winning biotech company, in a multi-year R&D partnership to harness expertise and proprietary technology to reprogram aged 'senescent' cells.

L'Oréal also maintains ongoing collaborations with longevity leading experts including Dr. Andrea Maier of the National University of Singapore on the interplay between the skin and internal organs, Professor Andor Pivarcsi of Uppsala University on epigenetics and skin health, Professor Benjamin Loos of Stellenbosch University on autophagy of skin cells during aging, and Professor Rob Knight of University of California at San Diego on skin aging and the microbiome.

The Beauty and Longevity Convergence

Beauty is no longer about aesthetics alone. It is about health, biology, and the agency to design your own aging trajectory. L'Oréal's vision establishes this truth: skin health is longevity. Longevity is beauty. And together, they define vibrant healthy aging.