The agenda for the Skin, Bone & Muscle Mastermind is live. A full day of sessions across one Saturday in New York, on the science and the clinical protocols for skin, bone and muscle. Registration is open, and the programme below is the full published running order.

The Skin, Bone & Muscle Mastermind is a one day, physicians only conference on Saturday 24 October 2026 at Convene, 101 Park Avenue, New York. The sessions run from 8:45 AM to 4:30 PM, with a Friday evening Welcome Reception the night before and a Mastermind Dinner after the closing session.

The day is built around three tissues that age as one system, and the agenda treats them that way.

SKIN carries the largest block. Saranya Wyles, MD, PhD opens with Skin Regeneration: Stem Cells, Secretomes and Exosomes. Doris Day, MD follows with Topical Rapamycin and Rapalogs in Skin Longevity. Amanda Hill, MD, FAAD presents The Aging Face, Biomarkers and Protocol. The afternoon adds Latest devices protocol from Dan Belkin, MD, Procedure Parameters and Pigment Risk Across Skin Types from Naana Boakye, MD, CLD, MPH, FAAD, and Biostimulators, Polynucleotides and Growth Factors from Kay Durairaj, MD, FACS.

BONE & MUSCLE anchor the afternoon. Elizabeth Yurth, MD presents The GLP-1 Tax: Muscle and Bone on Incretin Therapy. Catherine Johnson, MD follows with Bone Loss: Screening, Markers and Sequencing. Neely Khan, MD, MS, FAAD covers Hormonal Transition and Collagen Loss.

Two sessions cut across all three tissues. James Peyer, PhD presents Gerotherapeutics for Skin, Muscle and Bone: The Pipeline, and Robert Hariri, MD, PhD presents Cellular Therapies: How Cell Products Are Actually Made.

David Luu, MD opens the day with longevitydocs.™ Vision 2026.

Seats are limited to 150. Attendance requires an MD, DO or MBBS.

What is the longevitydocs™ Mastermind?

The longevitydocs™ Mastermind is a physician-exclusive one-day conference in longevity medicine. The science, the clinic and the latest innovation in one full day, built for the physicians building, leading and researching this field.

The next edition is Skin, Bone & Muscle, in New York on Saturday October 24, 2026, with a welcome reception the evening before. Sessions are physicians only, in person and virtually. You leave with the keynotes, the protocols, the debate, and the network.

What is on the Skin, Bone & Muscle Mastermind agenda?

A full day of sessions opening with longevitydocs.™ Vision 2026 and closing on biostimulators, with networking breaks and a seated lunch. Evidence first, protocols second.

Friday October 23: welcome reception

5:30 PM to 7:30 PM. Mocktails and light bites in a casual, conversational setting before Mastermind day. You meet a dozen physicians before the first session starts. Included with every ticket.

Saturday October 24: morning sessions

• 8:00 AM · Registration and breakfast. Informal morning networking.

• 8:45 AM · longevitydocs.™ Vision 2026. David Luu, MD.

• 9:00 AM · Skin Regeneration: Stem Cells, Secretomes and Exosomes. 
  Learning Objectives:
  - Describe how stem cells, platelet rich plasma, secretomes and extracellular vesicles act on skin, including paracrine signaling and cellular senescence.
  - Differentiate product categories by source, characterization and regulatory status, including the line between a topical cosmetic and an injected biologic.
  - Define valid endpoints in regenerative dermatology: histology, validated grading scales, senescence biomarkers, blinded vehicle-controlled design.
  
  

• 9:20 AM · Gerotherapeutics for Skin, Muscle and Bone: The Pipeline. James Peyer, PhD.
  Learning Objectives:
  - Which aging-targeted drug classes have human data and which are still preclinical: senolytics, mTOR modulators, myostatin/activin inhibitors, NAD+ biology.
  - How trials are designed when aging is not an FDA-recognized indication.
  - Realistic timelines to clinical availability.
  
  

• 9:50 AM · Cellular Therapies: How Cell Products Are Actually Made. Robert Hariri, MD, PhD.
  Learning Objectives:
  - How placental, MSC, iPSC-derived and Muse cells differ in biology and clinical maturity.
  - GMP manufacturing from donor screening to potency assays and release criteria.
  - The line between a Section 351 biologic and a Section 361 product, and when an IND is required.
  
  

• 10:10 AM · Topical Rapamycin and Rapalogs in Skin Longevity. Doris Day, MD.
  Learning Objectives:
  - Explain mTORC1 versus mTORC2 inhibition and why intermittent dosing matters.
  - Summerize human data for topical and low-dose systemic sirolimus in skin aging, and the limits of that data.
  - Apply a monitoring approach: lipids, glucose, CBC, infection risk, CYP3A4 interactions.
  - Identify patients who should not receive it, including perioperative patients given impaired wound healing.
  

• 10:30 AM · Coffee break. Connect and collaborate.

• 10:50 AM · The Aging Face, Biomarkers and Protocol. Amanda Hill, MD, FAAD.
  Learning Objectives:
  - Assess the aging face as three structural layers: bone, fat, dermis.
  - Sequence topicals, devices, injectables and systemic support, and place regenerative products according to current evidence.
  - Match the intervention to the patient's dominant driver of aging.
  - Recognize perception drift in the patient and in the physician.
  

• 11:10 AM · Session to be announced.

lunch

12:00 PM to 2:00 PM. Two hours, seated, in the venue, with nowhere else to be. This is when the community actually meets, and where most collaborations start.

afternoon sessions

• 2:00 PM · The GLP-1 Tax: Muscle and Bone on Incretin Therapy. Elizabeth Yurth, MD.
  Learning Objectives:
  - Quantify the lean mass fraction of weight lost in the major GLP-1 trials and the factors that modify it.
  - Diagnose sarcopenia using EWGSOP2 criteria: grip strength, chair stand, gait speed, appendicular lean mass.
  - Build a baseline and follow-up protocol: body composition, grip strength, DXA in at-risk patients.
  - Prescribe protein targets and resistance training alongside the drug, and adjust titration speed.
  - Appraise the evidence and current FDA compounding status of hormonal and peptide interventions for muscle.
  

• 2:30 PM · Bone Loss: Screening, Markers and Sequencing. Catherine Johnson, MD.

  Learning Objectives:
  - Apply screening criteria by age, sex, menopausal status and risk factors, including earlier screening in high-risk patients.
  - Interpret DXA, TBS and FRAX together, and state the limits of bone turnover markers.
  - Select among antiresorptive and anabolic agents and sequence them correctly.
  - Prescribe loading exercise, protein, vitamin D and calcium at evidence-based doses.
  

• 2:50 PM · Hormonal Transition and Collagen Loss. Neely Khan, MD, MS, FAAD.
  Learning Objectives:
  - Describe the shared hormonal drivers of skin, bone and muscle decline at the menopausal transition.
  - Summerize the collagen loss trajectory in the early postmenopausal years and the factors that accelerate it.
  - Select topical and systemic interventions appropriate to a dermatology practice.
  - Identify when to co-manage or refer for systemic hormone therapy.
  

• 3:10 PM · Coffee break. Connect and collaborate.

• 3:30 PM · Latest devices protocol. Dan Belkin, MD.
  Learning Objectives:
  - Match laser, radiofrequency and ultrasound modalities to tissue target and indication.
  - Identify the parameters that determine outcome: fluence, pulse duration, density, depth, passes.
  - Combine and sequence modalities safely, and state where safety data are missing.
  - Set treatment intervals based on tissue remodeling timelines.
  

• 3:50 PM · Procedure Parameters and Pigment Risk Across Skin Types. Naana Boakye, MD, CLD, MPH, FAAD.
  Learning Objectives:
  - Adjust device, injectable and topical protocols for Fitzpatrick IV to VI skin.
  - Rank common procedures by real pigment risk.
  - Apply the parameter changes and pre- and post-treatment regimens that reduce post-inflammatory hyperpigmentation.
  - Counsel patients on risk and obtain informed consent specific to skin type.
  

• 4:10 PM · Biostimulators, Polynucleotides and Growth Factors. Kay Durairaj, MD, FACS.
  Learning Objectives:
  - Assign an evidence tier to each biostimulator class by trial quality and endpoint.
  - Compare polynucleotides with established biostimulators and growth factors, and state their US regulatory status.
  - Select interval, injection plane and combinations for each class.
  - Build a regenerative menu that holds up to peer review.
  

• 4:30 PM · Closing networking. Through to 5:30 PM.

Mastermind dinner

6:00 PM. Two long tables at Zuma once the sessions are done. An intimate post-Mastermind dinner where the day's insights continue over food and peer-level conversation. Community and friendships are built. Add-on with limited seats.

Who is on the Mastermind faculty?

Our expert faculty are all practising physicians and scientists in the field: Doris Day, MD; Saranya Wyles, MD, PhD; Dan Belkin, MD; Naana Boakye, MD, CLD, MPH, FAAD; Kay Durairaj, MD, FACS; Amanda Hill, MD, FAAD; Neely Khan, MD, MS, FAAD; Elizabeth Yurth, MD; Catherine Johnson, MD; and James Peyer, PhD. Robert Hariri, MD, PhD presents on cellular therapies, and David Luu, MD opens the day.

What should I expect?

WELCOME RECEPTION • FRIDAY OCT 23

You meet a dozen physicians before the first session starts. Mocktails, light bites, and the people you came for, included with every ticket.

KEYNOTES & PANELS • SATURDAY OCT 24

A full day of sessions on skin, bone and muscle, evidence first and protocols second. 

The Lounge  

Breakfast, coffee and lunch happen in one room, so the conversations carry between sessions. You see the innovations your patients ask about, beside the people who built them. Open 8:00 AM to 5:30 PM.

HEALTHY LUNCH 

Two hours, seated, in the venue, with nowhere else to be. This is when the community actually meets, and where most collaborations start.

MASTERMIND DINNER  

Two long tables at Zuma, once the sessions are done. Community and friendship, built behind closed doors and off the record.

Digital replay

Sessions stream live for virtual tickets and are recorded in full. Every replay lands on longevitydocs.ai, included with every ticket, yours to keep.

Where is the Mastermind held?

Convene, 101 Park Avenue, New York, NY 10017, from 8:00 AM to 6:00 PM. The Saturday dinner is at Zuma NYC. The recommended hotel is the NH Collection New York Madison Avenue, 22 East 38th Street.

Who can attend, and what does a ticket cost?

Physicians only. Attendance requires certification that you are an MD, DO or hold an MBBS. The sessions are physicians only, in person and virtually. Spouses and guests can join the Saturday dinner with an additional ticket.

• Physician Pass, $499. Friday reception, all Saturday sessions, the Lounge, breakfast, coffee and lunch, and the digital replay.

• Physician Pass with Networking Dinner, $650. Adds a seat at the Saturday dinner at Zuma.

• Clinic Collective Pass, $1,000. Admits three physicians from one practice.

• Clinic Collective Pass with Networking Dinner, $1,450. Admits three physicians, with dinner seats.

Candidates in the Certified longevitydocs™ (CLD) program receive a 20% tuition benefit for 12 months on select offerings, including live and virtual Masterminds.

Can I attend the Mastermind virtually?

Yes. Sessions stream live to virtual ticket holders and are recorded in full, with every replay available on longevitydocs.ai for both in-person and virtual attendees. The in-room elements, meaning the reception, the Lounge, the seated lunch and the dinner, are in person only.

Keep reading

• The First Certified longevitydoc: Dr. Naana Boakye, MD, CLD, MPH
  Mastermind faculty, and the first physician through the certification.

• How Longevity Medicine Certification Propels Your Practice: The ROI
  What the credential changes in referrals, positioning and revenue.

• The Lexicon: The Living Library of Longevity Medicine
  A standardized definition for every concept in the field, with the publications behind it.

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